What formula does this calculator use for CrCl?

This calculator uses the Cockcroft-Gault equation, which is the standard for estimating renal function for drug dosing.

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Creatinine Clearance Calculator

Estimate glomerular filtration rate (GFR) using creatinine clearance, vital for assessing kidney function and drug dosing.

Kidney function is a critical factor in how the body processes and eliminates many medications. When the kidneys are not functioning at full capacity, drugs can accumulate to toxic levels. The Creatinine Clearance (CrCl) estimate provides a window into the kidneys' filtration rate, allowing clinicians to safely adjust dosages for patients with renal impairment.

Educational use only. This tool does not replace clinical judgment or local protocols.

Age (years)

Weight (kg)

Serum creatinine

Creatinine unit

Sex

Estimated CrCl (Cockcroft-Gault)

64.5mL/min

Estimated CrCl is 64.5 mL/min (Cockcroft-Gault)

((140 - Age) * Weight) / (72 * SCr_mgdl)

Age (years)65

Weight (kg)70 kg

Serum creatinine100 µmol/L

SexMale

工作原理

The Cockcroft-Gault formula uses age, weight, and serum creatinine levels, with a 15% reduction factor for female patients to account for lower average muscle mass.

计算公式

CrCl = [(140-age) × weight] / (72 × SCr) {× 0.85 if female}

Calculation Examples

1. **Male**: 60 years old, 80kg, SCr 1.2 mg/dL. CrCl = **74 mL/min**. 2. **Female**: 60 years old, 80kg, SCr 1.2 mg/dL. CrCl = **63 mL/min**.

Why use this tool in your daily life?

Preventing renal toxicity. This service provides the exact data needed to 'dose-adjust' medications, protecting patients from the permanent kidney damage or systemic toxicity caused by over-prescribing.

Frequently Asked Questions

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