What formula does this calculator use for CrCl?

This calculator uses the Cockcroft-Gault equation, which is the standard for estimating renal function for drug dosing.

医疗DoctorNephrologistPharmacist

Creatinine Clearance Calculator

Estimate glomerular filtration rate (GFR) using creatinine clearance, vital for assessing kidney function and drug dosing.

Kidney function is a critical factor in how the body processes and eliminates many medications. When the kidneys are not functioning at full capacity, drugs can accumulate to toxic levels. The Creatinine Clearance (CrCl) estimate provides a window into the kidneys' filtration rate, allowing clinicians to safely adjust dosages for patients with renal impairment.

仅供教育用途。该工具不能取代临床判断或当地协议。仅供教育用途。该工具不能取代临床判断或当地协议。

Age (years)

重量（公斤）

Serum creatinine

Creatinine unit

性别

Estimated CrCl (Cockcroft-Gault)

64.5mL/min

Estimated CrCl is 64.5 mL/min (Cockcroft-Gault)

((140 - Age) * Weight) / (72 * SCr_mgdl)

Age (years)65

重量（公斤）70 kg

Serum creatinine100 µmol/L

性别Male

工作原理

The Cockcroft-Gault formula uses age, weight, and serum creatinine levels, with a 15% reduction factor for female patients to account for lower average muscle mass.

计算公式

CrCl = [(140-age) × weight] / (72 × SCr) {× 0.85 if F}

计算示例

1. **Male**: 60y, 80kg, SCr 1.2 = **74 mL/min**.

为什么在日常生活中使用这个工具？

预防肾毒性。该服务提供“剂量调整”药物所需的准确数据，保护患者免受过度处方引起的永久性肾损伤或全身毒性。预防肾毒性。该服务提供“剂量调整”药物所需的准确数据，保护患者免受过度处方引起的永久性肾损伤或全身毒性。

常见问题解答

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