Why do we correct calcium for albumin?

About half of serum calcium is bound to albumin. If albumin levels are low, the total measured calcium will be low even if the active (ionized) calcium is normal.

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TıbbiDoctorMedical Laboratory Scientist

Corrected Calcium Calculator

Calculate serum calcium levels corrected for albumin, providing a more accurate reflection of physiologically active calcium.

Calcium is essential for bone health, nerve signaling, and muscle function. However, standard lab tests measure 'total' calcium, which includes calcium bound to proteins like albumin. If albumin is low, the total calcium result can be misleading. This calculator 'corrects' the calcium level to show what it would be if the patient had normal albumin levels.

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Measured calcium

Albumin (g/L)

Calcium units

Albumin input stays g/L; conversion handled automatically.

Corrected calcium

2.2mmol/L

Corrected Calcium is 2.2 mmol/L

Ca + 0.02 * (40 - Alb) = 2.1 + 0.02 * (40 - 35)

Measured calcium2.1 mmol/L

Albumin (g/L)35 g/L

Unitsmmol/L

Nasıl Çalışır

The tool uses the standard Payne formula, which adds a correction factor for every unit that the patient's albumin is below the normal reference (usually 4.0 g/dL or 40 g/L).

Hesaplama Formülü

Ca_corr = Ca_meas + 0.8 × (4.0 - Albumin)

Hesaplama Örnekleri

1. **Low Protein**: Ca 8.0, Albumin 2.0 = **9.6 (Normal)**.

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