High-sensitivity C-reactive protein (hsCRP) is a blood marker for inflammation. Chronic inflammation in the arteries is a major contributor to atherosclerosis and heart attacks.

Who should use the Reynolds Risk Score?

It is particularly useful for people with intermediate or low traditional risk scores who have a strong family history of heart disease or known inflammatory conditions.

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Health & Fitness

Reynolds Risk Score – Advanced Heart Risk Service | CalcTools

Predict your 10-year cardiovascular risk using hsCRP and family history. An advanced clinical model for improved accuracy.

Standard risk calculators often miss high-risk individuals because they only look at traditional factors like cholesterol and blood pressure. The Reynolds Risk Score was developed to improve prediction accuracy by including two critical additional markers: high-sensitivity C-reactive protein (hsCRP), a measure of systemic inflammation, and a detailed family history of premature heart disease. This model is particularly effective for individuals who might be classified as 'low risk' by other tools but actually carry significant underlying vulnerability. Our Reynolds Risk service provides a sophisticated assessment for those seeking the highest level of heart health insight.

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How it Works

The calculator integrates traditional risk factors with your hsCRP level and parental history using a specialized algorithm. This multi-layered approach provides a more comprehensive view of your cardiovascular 'age.'

Calculation Formula

Reynolds Risk Score Algorithm

Calculation Examples

1. **Inflammation**: An individual with normal cholesterol but high hsCRP may find their risk is significantly higher than a standard BMI/BP check would indicate.

Why use this tool in your daily life?

Don't settle for a basic health check. This service uses advanced clinical markers to ensure that hidden risks are identified, giving you the best possible chance to prevent a heart attack or stroke before it happens.